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Semax vs Semax & Selank

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Semax

Semax is a synthetic peptide derived from ACTH (adrenocorticotropic hormone). Developed in Russia as a nootropic and neuroprotective agent.

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Semax & Selank

A nootropic combination pairing two Russian-developed peptides for cognitive enhancement. Semax provides stimulating focus and neuroprotection while Selank offers anxiolytic and mood-stabilizing effects, creating a balanced cognitive enhancement stack.

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Side-by-Side Comparison

AspectSemaxSemax & Selank
MechanismEnhances BDNF expression, modulates dopamine and serotonin systems, and provides neuroprotective effects. Increases attention, memory formation, and learning.Semax enhances BDNF expression and modulates dopamine and serotonin systems for improved focus, memory, and neuroprotection. Selank affects BDNF and GABA systems, providing anxiolytic effects and immune modulation. Together they support cognitive function while managing stress and anxiety.
Typical DosageIntranasal: 200-600mcg 2-3 times daily. Higher doses (up to 1mg) used in clinical settings for stroke recovery.Semax: 200-600mcg intranasally 2-3 times daily. Selank: 250-500mcg intranasally 2-3 times daily. Can be used together or alternated based on needs.
AdministrationPrimarily administered intranasally. N-Acetyl Semax Amidate (NASA) is a modified version with enhanced stability and potency.Primarily administered intranasally for rapid brain uptake. N-Acetyl versions (NA-Semax, NA-Selank) offer enhanced stability and potency. Can also be injected subcutaneously.
Side EffectsGenerally well-tolerated. May cause mild irritability or hair shedding in some users.Semax may cause mild irritability or hair shedding. Selank may cause mild fatigue or nasal irritation. Both are generally well-tolerated.
Best For

What They Have in Common

Both Semax and Semax & Selank are commonly used for:

Key Differences

Unique to Semax:

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