Semax

Semax is a synthetic peptide derived from ACTH (adrenocorticotropic hormone). Developed in Russia as a nootropic and neuroprotective agent.

Mechanism of Action

Enhances BDNF expression, modulates dopamine and serotonin systems, and provides neuroprotective effects. Increases attention, memory formation, and learning.

Typical Dosage (Research)

Intranasal: 200-600mcg 2-3 times daily. Higher doses (up to 1mg) used in clinical settings for stroke recovery.

Primarily administered intranasally. N-Acetyl Semax Amidate (NASA) is a modified version with enhanced stability and potency.

Side Effects & Risks

Generally well-tolerated. May cause mild irritability or hair shedding in some users.

May affect thyroid function with prolonged use. Limited clinical data outside Russia.

Who Uses Semax

Students, professionals seeking cognitive enhancement, those recovering from brain injury.