Best Peptides for Sexual Health
Peptides that support libido, sexual function, and overall sexual wellness.
Top Peptides for Sexual Health
| Peptide | Evidence | Use Case | Actions |
|---|---|---|---|
| PT-141 (Bremelanotide)Top Choice PT-141, also known as Bremelanotide, is a synthetic peptide analog of alpha-melanocyte-stimulating hormone. It is the only FDA-approved treatment for hypoactive sexual desire disorder (HSDD) in premenopausal women. | high | FDA-approved for HSDD, primary indication | |
| Melanotan IITop Choice Melanotan II is a synthetic peptide analog of α-MSH with broader receptor activity than Melanotan I. It produces tanning effects and has notable effects on sexual function and appetite suppression. | medium | MC3R/MC4R activation enhances libido and erectile function | |
| Kisspeptin-10Top Choice Kisspeptin-10 is the active fragment of kisspeptin, a hormone that plays a crucial role in initiating puberty and regulating reproductive function. It acts upstream of GnRH in the hypothalamic-pituitary-gonadal axis. | medium | Upstream regulator of reproductive hormone cascade | |
| GonadorelinTop Choice Gonadorelin is a synthetic form of gonadotropin-releasing hormone (GnRH). It stimulates the pituitary to release luteinizing hormone (LH) and follicle-stimulating hormone (FSH), supporting natural hormone production. | high | Maintains natural hormone production and fertility during HRT |
PT-141, also known as Bremelanotide, is a synthetic peptide analog of alpha-melanocyte-stimulating hormone. It is the only FDA-approved treatment for hypoactive sexual desire disorder (HSDD) in premenopausal women.
FDA-approved for HSDD, primary indication
Melanotan II is a synthetic peptide analog of α-MSH with broader receptor activity than Melanotan I. It produces tanning effects and has notable effects on sexual function and appetite suppression.
MC3R/MC4R activation enhances libido and erectile function
Kisspeptin-10 is the active fragment of kisspeptin, a hormone that plays a crucial role in initiating puberty and regulating reproductive function. It acts upstream of GnRH in the hypothalamic-pituitary-gonadal axis.
Upstream regulator of reproductive hormone cascade
Gonadorelin is a synthetic form of gonadotropin-releasing hormone (GnRH). It stimulates the pituitary to release luteinizing hormone (LH) and follicle-stimulating hormone (FSH), supporting natural hormone production.
Maintains natural hormone production and fertility during HRT