Thymulin vs Alpha-Defensin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Thymulin

Thymulin (Facteur Thymique Sérique) is a zinc-dependent nonapeptide hormone produced by thymic epithelial cells. It plays important roles in T-cell differentiation and immune system maturation.

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Alpha-Defensin

Alpha-defensins are small cationic peptides that are key components of the innate immune system. They have broad-spectrum antimicrobial activity against bacteria, fungi, and some viruses.

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Side-by-Side Comparison

AspectThymulinAlpha-Defensin
MechanismRequires zinc for biological activity. Promotes T-cell differentiation, modulates cytokine production, and influences neuroendocrine function. Levels decline significantly with age.Insert into microbial membranes to form pores, leading to cell death. Also have immunomodulatory effects including chemotaxis of immune cells and cytokine modulation.
Typical DosageResearch protocols vary. Often studied alongside zinc supplementation. Typical research doses in the microgram range.Research compound - dosing varies by application. Typically studied in laboratory and early clinical research settings rather than for general use.
AdministrationSubcutaneous or intramuscular injection in research settings. Requires adequate zinc status for activity.Various routes studied including topical, local injection, and systemic administration depending on application.
Side EffectsLimited data on exogenous administration. Theoretical effects on immune function require monitoring.Limited human use data. May cause local inflammation. Potential for immune activation effects.
Best For

What They Have in Common

Both Thymulin and Alpha-Defensin are commonly used for:

Key Differences

Unique to Thymulin:

Unique to Alpha-Defensin:

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