Thymalin vs Thymosin Alpha-1

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Thymalin

Thymalin is a polypeptide preparation derived from calf thymus. Developed in Russia, it has been used for decades to support immune function and has shown potential anti-aging effects in long-term studies.

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Thymosin Alpha-1

Thymosin Alpha-1 is a peptide naturally produced by the thymus gland that plays a crucial role in immune system modulation. It is approved in over 35 countries for various conditions including hepatitis B and C.

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Side-by-Side Comparison

AspectThymalinThymosin Alpha-1
MechanismRegulates the ratio of T-cell subpopulations, stimulates cellular immunity, and enhances phagocytosis. Also affects neuroendocrine regulation and may influence melatonin production.Enhances T-cell function and maturation, stimulates dendritic cell activity, and modulates cytokine production. Promotes the differentiation of stem cells into mature T lymphocytes.
Typical DosageClinical protocols: 5-20mg daily intramuscularly for 3-10 days. Often cycled 1-2 times per year for maintenance.Clinical dosing typically ranges from 1.6mg to 6.4mg administered subcutaneously 2-3 times weekly. Research protocols may vary.
AdministrationIntramuscular injection. Usually administered in short courses rather than continuously. Often combined with Epithalamin for anti-aging protocols.Subcutaneous injection. Often used in cycles or as part of comprehensive immune support protocols.
Side EffectsGenerally well-tolerated. May cause injection site reactions or temporary flu-like symptoms as immune function is modulated.Generally well-tolerated. Rare side effects include injection site reactions, mild flu-like symptoms, and temporary fatigue.
Best For

What They Have in Common

Both Thymalin and Thymosin Alpha-1 are commonly used for:

Key Differences

Unique to Thymalin:

Unique to Thymosin Alpha-1:

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