SHLP2 vs Thymalin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

SHLP2

SHLP2 (Small Humanin-Like Peptide 2) is a mitochondrial-derived peptide similar to humanin. It has shown insulin-sensitizing and cytoprotective effects in research, with potential metabolic benefits.

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Thymalin

Thymalin is a polypeptide preparation derived from calf thymus. Developed in Russia, it has been used for decades to support immune function and has shown potential anti-aging effects in long-term studies.

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Side-by-Side Comparison

AspectSHLP2Thymalin
MechanismEnhances insulin sensitivity and glucose uptake. Provides cytoprotective effects similar to humanin. May act through similar but distinct receptor pathways.Regulates the ratio of T-cell subpopulations, stimulates cellular immunity, and enhances phagocytosis. Also affects neuroendocrine regulation and may influence melatonin production.
Typical DosageResearch compound with doses in the microgram to low milligram range studied in animal models. Human dosing not established.Clinical protocols: 5-20mg daily intramuscularly for 3-10 days. Often cycled 1-2 times per year for maintenance.
AdministrationSubcutaneous or intraperitoneal injection in research settings. Various SHLP analogs (1-6) have different properties.Intramuscular injection. Usually administered in short courses rather than continuously. Often combined with Epithalamin for anti-aging protocols.
Side EffectsLimited data. Animal studies suggest good tolerability. May affect glucose metabolism.Generally well-tolerated. May cause injection site reactions or temporary flu-like symptoms as immune function is modulated.
Best For

What They Have in Common

Both SHLP2 and Thymalin are commonly used for:

Key Differences

Unique to SHLP2:

Unique to Thymalin:

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