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Pinealon vs Sermorelin & GHRP-2 & GHRP-6

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Pinealon

Pinealon is a short synthetic peptide developed from research on the pineal gland. It has shown neuroprotective and cognitive-enhancing properties in animal studies.

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Sermorelin & GHRP-2 & GHRP-6

A powerful tri-blend combining Sermorelin (a GHRH analog) with two growth hormone releasing peptides. This combination produces significantly greater GH release than any single peptide, with studies showing up to 54-fold increases in pulsatile GH secretion.

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Side-by-Side Comparison

AspectPinealonSermorelin & GHRP-2 & GHRP-6
MechanismPenetrates cell membranes and interacts with DNA to regulate gene expression related to neuronal survival and function. May support pineal gland function and melatonin production.Sermorelin stimulates the pituitary via GHRH receptors, while GHRP-2 and GHRP-6 act as ghrelin mimetics on different receptor subtypes. The combination creates synergistic GH release through multiple complementary pathways. GHRP-6 also strongly stimulates appetite.
Typical DosageTypical dosing: 10-20mg daily, taken in divided doses. Often used in cycles of 10-20 days.Typical protocols: Sermorelin 100-300mcg, GHRP-2 100-300mcg, GHRP-6 100-300mcg. Often administered 2-3 times daily, 30 minutes before meals or at bedtime.
AdministrationCan be taken orally (capsules) or sublingually. Best absorbed on an empty stomach. Often combined with other neuroprotective peptides.Subcutaneous injection. Best administered fasted or before sleep to maximize natural GH cycle. The three peptides can be mixed together or administered separately.
Side EffectsGenerally well-tolerated. Limited reported side effects. May affect sleep patterns initially.Increased hunger (especially from GHRP-6), water retention, facial flushing, nausea, tingling, potential increases in cortisol and prolactin levels.
Best For

What They Have in Common

Both Pinealon and Sermorelin & GHRP-2 & GHRP-6 are commonly used for:

Key Differences

Unique to Pinealon:

Unique to Sermorelin & GHRP-2 & GHRP-6:

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