NA-Semax Amidate vs Semax

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

NA-Semax Amidate

NA-Semax Amidate (N-Acetyl Semax Amidate) is a modified version of Semax with enhanced stability and potency. Also known as NASA, it provides stronger and longer-lasting nootropic effects than standard Semax.

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Semax

Semax is a synthetic peptide derived from ACTH (adrenocorticotropic hormone). Developed in Russia as a nootropic and neuroprotective agent.

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Side-by-Side Comparison

AspectNA-Semax AmidateSemax
MechanismMaintains Semax's core actions on BDNF, NGF, and monoamine systems with improved pharmacokinetics. The modifications enhance CNS penetration and extend duration of action.Enhances BDNF expression, modulates dopamine and serotonin systems, and provides neuroprotective effects. Increases attention, memory formation, and learning.
Typical DosageIntranasal: 100-600mcg 1-2 times daily. Start with lower doses as it's more potent than standard Semax.Intranasal: 200-600mcg 2-3 times daily. Higher doses (up to 1mg) used in clinical settings for stroke recovery.
AdministrationIntranasal spray is most common. Can be used sublingually. More stable than standard Semax in solution.Primarily administered intranasally. N-Acetyl Semax Amidate (NASA) is a modified version with enhanced stability and potency.
Side EffectsMay cause irritability, hair shedding (rare), or overstimulation at high doses. Generally well-tolerated.Generally well-tolerated. May cause mild irritability or hair shedding in some users.
Best For

What They Have in Common

Both NA-Semax Amidate and Semax are commonly used for:

Key Differences

Unique to Semax:

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