Alpha-Defensin vs Cerebrolysin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Alpha-Defensin

Alpha-defensins are small cationic peptides that are key components of the innate immune system. They have broad-spectrum antimicrobial activity against bacteria, fungi, and some viruses.

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Cerebrolysin

Cerebrolysin is a mixture of low-molecular-weight neuropeptides and free amino acids derived from purified pig brain proteins. It is approved in many countries for stroke, traumatic brain injury, and dementia.

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Side-by-Side Comparison

AspectAlpha-DefensinCerebrolysin
MechanismInsert into microbial membranes to form pores, leading to cell death. Also have immunomodulatory effects including chemotaxis of immune cells and cytokine modulation.Contains multiple neurotrophic factors that promote neuroplasticity, reduce neuronal apoptosis, and support synaptic function. Has both neurotrophic and neuroprotective properties.
Typical DosageResearch compound - dosing varies by application. Typically studied in laboratory and early clinical research settings rather than for general use.Clinical dosing: 10-30ml IV daily for acute conditions. Research use: 5-10ml IM daily for cognitive enhancement. Treatment courses typically last 10-20 days.
AdministrationVarious routes studied including topical, local injection, and systemic administration depending on application.Administered via intramuscular or intravenous injection. IV administration is typically used in clinical settings. IM can be used for research purposes.
Side EffectsLimited human use data. May cause local inflammation. Potential for immune activation effects.Generally well-tolerated. May cause dizziness, headache, sweating, or injection site reactions. Rare cases of agitation or confusion.
Best For

What They Have in Common

Both Alpha-Defensin and Cerebrolysin are commonly used for:

Key Differences

Unique to Alpha-Defensin:

Unique to Cerebrolysin:

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