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Alpha-Defensin vs BPC-157 & TB-500 & GHK-Cu

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Alpha-Defensin

Alpha-defensins are small cationic peptides that are key components of the innate immune system. They have broad-spectrum antimicrobial activity against bacteria, fungi, and some viruses.

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BPC-157 & TB-500 & GHK-Cu

The complete healing triad combining the Wolverine Stack with GHK-Cu (copper peptide) for comprehensive tissue repair. This blend addresses healing at multiple levels: cellular repair, collagen synthesis, and tissue regeneration.

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Side-by-Side Comparison

AspectAlpha-DefensinBPC-157 & TB-500 & GHK-Cu
MechanismInsert into microbial membranes to form pores, leading to cell death. Also have immunomodulatory effects including chemotaxis of immune cells and cytokine modulation.BPC-157 promotes angiogenesis and growth factor expression. TB-500 enhances cell migration and reduces inflammation. GHK-Cu activates genes involved in tissue remodeling, stimulates collagen and elastin production, and provides antioxidant protection. Together they support healing from multiple angles.
Typical DosageResearch compound - dosing varies by application. Typically studied in laboratory and early clinical research settings rather than for general use.Typical protocol: BPC-157 250-500mcg daily, TB-500 2-2.5mg twice weekly, GHK-Cu 1-2mg daily or applied topically for skin applications.
AdministrationVarious routes studied including topical, local injection, and systemic administration depending on application.BPC-157 and TB-500 via subcutaneous injection. GHK-Cu can be injected subcutaneously or used topically depending on the target area. Systemic and local administration may be combined.
Side EffectsLimited human use data. May cause local inflammation. Potential for immune activation effects.Generally well-tolerated. Possible injection site irritation, mild fatigue, or temporary skin discoloration with GHK-Cu.
Best For

What They Have in Common

Both Alpha-Defensin and BPC-157 & TB-500 & GHK-Cu are commonly used for:

Key Differences

Unique to Alpha-Defensin:

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