Adamax vs Semax

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Adamax

Adamax is a modified version of Semax with an adamantane group attached, designed to enhance its nootropic effects and extend duration of action compared to standard Semax.

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Semax

Semax is a synthetic peptide derived from ACTH (adrenocorticotropic hormone). Developed in Russia as a nootropic and neuroprotective agent.

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Side-by-Side Comparison

AspectAdamaxSemax
MechanismSimilar to Semax - enhances BDNF expression and modulates dopamine/serotonin systems. The adamantane modification may increase lipophilicity and CNS penetration.Enhances BDNF expression, modulates dopamine and serotonin systems, and provides neuroprotective effects. Increases attention, memory formation, and learning.
Typical DosageIntranasal: 100-500mcg 1-2 times daily. Lower doses than standard Semax may be effective due to enhanced potency.Intranasal: 200-600mcg 2-3 times daily. Higher doses (up to 1mg) used in clinical settings for stroke recovery.
AdministrationIntranasal spray is most common route. More stable than standard Semax. Often used for acute cognitive enhancement.Primarily administered intranasally. N-Acetyl Semax Amidate (NASA) is a modified version with enhanced stability and potency.
Side EffectsSimilar to Semax - possible irritability, hair shedding, or overstimulation. May have stronger effects than standard Semax.Generally well-tolerated. May cause mild irritability or hair shedding in some users.
Best For

What They Have in Common

Both Adamax and Semax are commonly used for:

Key Differences

Unique to Semax:

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