Ipamorelin

Ipamorelin is a selective growth hormone secretagogue that stimulates the release of growth hormone from the pituitary gland without significantly affecting cortisol or prolactin.

Mechanism of Action

Acts as a ghrelin mimetic, binding to the ghrelin receptor (GHS-R) in the pituitary to stimulate GH release. Highly selective with minimal effect on other hormones.

Typical Dosage (Research)

Typical dosing ranges from 200-300mcg administered 2-3 times daily, often combined with CJC-1295.

Subcutaneous injection. Best results when administered fasted or before sleep. Often stacked with GHRH peptides.

Side Effects & Risks

Generally well-tolerated. May cause mild headaches, lightheadedness, or increased hunger initially.

Long-term effects on natural GH production not fully characterized. Not approved for human use.

Who Uses Ipamorelin

Those seeking improved sleep, recovery, body composition, and anti-aging benefits.