SHLP2 vs Epitalon

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

SHLP2

SHLP2 (Small Humanin-Like Peptide 2) is a mitochondrial-derived peptide similar to humanin. It has shown insulin-sensitizing and cytoprotective effects in research, with potential metabolic benefits.

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Epitalon

Epitalon (Epithalon) is a synthetic tetrapeptide based on the natural peptide epithalamin, produced by the pineal gland. It is primarily studied for its effects on telomerase activation.

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Side-by-Side Comparison

AspectSHLP2Epitalon
MechanismEnhances insulin sensitivity and glucose uptake. Provides cytoprotective effects similar to humanin. May act through similar but distinct receptor pathways.Stimulates telomerase production, which can lengthen telomeres on DNA strands. May also regulate melatonin production and circadian rhythms.
Typical DosageResearch compound with doses in the microgram to low milligram range studied in animal models. Human dosing not established.Typical protocols: 5-10mg daily for 10-20 days, repeated 2-3 times per year.
AdministrationSubcutaneous or intraperitoneal injection in research settings. Various SHLP analogs (1-6) have different properties.Subcutaneous or intramuscular injection. Usually administered in cycles rather than continuously.
Side EffectsLimited data. Animal studies suggest good tolerability. May affect glucose metabolism.Generally well-tolerated. May affect sleep patterns initially.
Best For

What They Have in Common

Both SHLP2 and Epitalon are commonly used for:

Key Differences

Unique to SHLP2:

Unique to Epitalon:

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