Oxytocin vs Semax & Selank
A detailed comparison to help you understand the differences and choose the right peptide for your research goals.
Oxytocin
Oxytocin is a natural hormone produced in the hypothalamus, often called the 'love hormone' or 'bonding hormone.' It plays key roles in social bonding, childbirth, lactation, and stress regulation.
Full details →Semax & Selank
A nootropic combination pairing two Russian-developed peptides for cognitive enhancement. Semax provides stimulating focus and neuroprotection while Selank offers anxiolytic and mood-stabilizing effects, creating a balanced cognitive enhancement stack.
Full details →Side-by-Side Comparison
| Aspect | Oxytocin | Semax & Selank |
|---|---|---|
| Mechanism | Binds to oxytocin receptors in the brain and peripheral tissues. Promotes social bonding, reduces anxiety and stress response, and has various peripheral effects on smooth muscle contraction. | Semax enhances BDNF expression and modulates dopamine and serotonin systems for improved focus, memory, and neuroprotection. Selank affects BDNF and GABA systems, providing anxiolytic effects and immune modulation. Together they support cognitive function while managing stress and anxiety. |
| Typical Dosage | Intranasal: 20-40 IU (international units) for social/anxiolytic effects. Clinical uses (labor induction) require IV administration under medical supervision. | Semax: 200-600mcg intranasally 2-3 times daily. Selank: 250-500mcg intranasally 2-3 times daily. Can be used together or alternated based on needs. |
| Administration | Intranasal spray for behavioral effects. IV only in clinical settings. Sublingual also possible. Best used situationally rather than continuously. | Primarily administered intranasally for rapid brain uptake. N-Acetyl versions (NA-Semax, NA-Selank) offer enhanced stability and potency. Can also be injected subcutaneously. |
| Side Effects | Intranasal: headache, nasal irritation, drowsiness. May cause over-attachment or emotional sensitivity. IV (clinical): uterine hyperstimulation, water retention. | Semax may cause mild irritability or hair shedding. Selank may cause mild fatigue or nasal irritation. Both are generally well-tolerated. |
| Best For |
What They Have in Common
Both Oxytocin and Semax & Selank are commonly used for: