GHRP-2 vs GHRP-6

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

GHRP-2

Growth Hormone Releasing Peptide 2 (GHRP-2) is considered one of the most potent GHRPs available. It provides strong GH release with moderate hunger increase compared to GHRP-6.

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GHRP-6

Growth Hormone Releasing Peptide 6 (GHRP-6) is one of the first synthetic growth hormone secretagogues discovered. It stimulates significant GH release but is known for causing intense hunger.

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Side-by-Side Comparison

AspectGHRP-2GHRP-6
MechanismBinds to the ghrelin receptor (GHS-R) to stimulate GH release from the pituitary. Also has some direct effects on the hypothalamus. Causes less appetite increase than GHRP-6.Acts as a ghrelin mimetic, binding to the GHS-R receptor in the pituitary and hypothalamus. Stimulates GH release and also significantly increases appetite by mimicking ghrelin's hunger-signaling effects.
Typical DosageTypical dosing: 100-300mcg administered 2-3 times daily. Often stacked with GHRH peptides for enhanced GH release.Typical dosing: 100-300mcg administered 2-3 times daily. Often combined with GHRH peptides like CJC-1295 for synergistic effects.
AdministrationSubcutaneous injection on an empty stomach. Can be used at bedtime to enhance natural GH pulse during sleep.Subcutaneous injection. Best administered on an empty stomach. The strong hunger response can be beneficial for those trying to gain weight but challenging for cutting.
Side EffectsModerate hunger increase, water retention, potential prolactin and cortisol elevation (less than GHRP-6), tingling sensations.Intense hunger (most notable effect), water retention, increased cortisol and prolactin, tingling/numbness, and potential blood pressure changes.
Best For

What They Have in Common

Both GHRP-2 and GHRP-6 are commonly used for:

Key Differences

Unique to GHRP-2:

Unique to GHRP-6:

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