Epitalon vs TB-500

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Epitalon

Epitalon (Epithalon) is a synthetic tetrapeptide based on the natural peptide epithalamin, produced by the pineal gland. It is primarily studied for its effects on telomerase activation.

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TB-500

Thymosin Beta-4 (TB-500) is a naturally occurring peptide present in almost all human and animal cells. It plays a crucial role in tissue repair and regeneration.

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Side-by-Side Comparison

AspectEpitalonTB-500
MechanismStimulates telomerase production, which can lengthen telomeres on DNA strands. May also regulate melatonin production and circadian rhythms.TB-500 promotes cell migration and differentiation, regulates actin (a cell-building protein), and reduces inflammation. It supports the formation of new blood vessels and wound healing.
Typical DosageTypical protocols: 5-10mg daily for 10-20 days, repeated 2-3 times per year.Research protocols typically use 2-2.5mg twice weekly during the loading phase, followed by maintenance dosing of 2mg every 2 weeks.
AdministrationSubcutaneous or intramuscular injection. Usually administered in cycles rather than continuously.Administered via subcutaneous or intramuscular injection. Some protocols suggest injection near injury sites.
Side EffectsGenerally well-tolerated. May affect sleep patterns initially.May cause temporary fatigue, headache, or localized irritation at injection sites.
Best For

Key Differences

Unique to Epitalon:

Unique to TB-500:

Detailed Analysis

Epitalon and TB-500 are used for different purposes and have limited overlap in their applications.

Which Should You Choose?

Choose Epitalon for Sleep Quality. Choose TB-500 for Muscle Growth, Recovery & Healing.

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