Epigen vs TB-500

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Epigen

Epigen is a member of the epidermal growth factor (EGF) family. It plays roles in skin regeneration and has been studied for wound healing and anti-aging applications.

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TB-500

Thymosin Beta-4 (TB-500) is a naturally occurring peptide present in almost all human and animal cells. It plays a crucial role in tissue repair and regeneration.

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Side-by-Side Comparison

AspectEpigenTB-500
MechanismBinds to and activates the EGF receptor (EGFR), promoting cell proliferation, migration, and differentiation. Involved in skin homeostasis and repair processes.TB-500 promotes cell migration and differentiation, regulates actin (a cell-building protein), and reduces inflammation. It supports the formation of new blood vessels and wound healing.
Typical DosageTopical: Typically used at low concentrations (ppm to low %) in cosmetic formulations. Research applications vary.Research protocols typically use 2-2.5mg twice weekly during the loading phase, followed by maintenance dosing of 2mg every 2 weeks.
AdministrationPrimarily topical application for skincare. Research may use other routes for systemic effects.Administered via subcutaneous or intramuscular injection. Some protocols suggest injection near injury sites.
Side EffectsTopical use generally well-tolerated. Theoretical concerns about promoting cell proliferation.May cause temporary fatigue, headache, or localized irritation at injection sites.
Best For

What They Have in Common

Both Epigen and TB-500 are commonly used for:

Key Differences

Unique to Epigen:

Unique to TB-500:

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