Epigen vs Palmitoyl Tetrapeptide-7

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Epigen

Epigen is a member of the epidermal growth factor (EGF) family. It plays roles in skin regeneration and has been studied for wound healing and anti-aging applications.

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Palmitoyl Tetrapeptide-7

Palmitoyl Tetrapeptide-7 is an anti-inflammatory peptide that reduces IL-6 secretion. Combined with Palmitoyl Tripeptide-1, it forms Matrixyl 3000, addressing both collagen production and inflammation.

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Side-by-Side Comparison

AspectEpigenPalmitoyl Tetrapeptide-7
MechanismBinds to and activates the EGF receptor (EGFR), promoting cell proliferation, migration, and differentiation. Involved in skin homeostasis and repair processes.Suppresses interleukin-6 (IL-6) production, reducing inflammation that contributes to skin aging. The anti-inflammatory effect complements collagen-stimulating peptides.
Typical DosageTopical: Typically used at low concentrations (ppm to low %) in cosmetic formulations. Research applications vary.Topical: Usually combined with Palmitoyl Tripeptide-1 at similar concentrations (2-4%) in the Matrixyl 3000 complex.
AdministrationPrimarily topical application for skincare. Research may use other routes for systemic effects.Topical application with other anti-aging actives. The palmitoyl group enhances delivery into the skin.
Side EffectsTopical use generally well-tolerated. Theoretical concerns about promoting cell proliferation.Excellent tolerability profile. Anti-inflammatory properties may actually soothe sensitive skin.
Best For

What They Have in Common

Both Epigen and Palmitoyl Tetrapeptide-7 are commonly used for:

Key Differences

Unique to Epigen:

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