Cortexin vs Oxytocin
A detailed comparison to help you understand the differences and choose the right peptide for your research goals.
Cortexin
Cortexin is a polypeptide complex derived from pig brain cortex, used clinically in Russia and Eastern Europe for neurological conditions including stroke recovery, traumatic brain injury, and cognitive decline.
Full details →Oxytocin
Oxytocin is a natural hormone produced in the hypothalamus, often called the 'love hormone' or 'bonding hormone.' It plays key roles in social bonding, childbirth, lactation, and stress regulation.
Full details →Side-by-Side Comparison
| Aspect | Cortexin | Oxytocin |
|---|---|---|
| Mechanism | Contains a mixture of neuropeptides and amino acids that support neuronal metabolism, provide neuroprotection, and enhance synaptic transmission. Specific mechanisms not fully characterized. | Binds to oxytocin receptors in the brain and peripheral tissues. Promotes social bonding, reduces anxiety and stress response, and has various peripheral effects on smooth muscle contraction. |
| Typical Dosage | Clinical protocols: 10mg intramuscularly once daily for 10-20 days. May be repeated after 3-6 month interval. | Intranasal: 20-40 IU (international units) for social/anxiolytic effects. Clinical uses (labor induction) require IV administration under medical supervision. |
| Administration | Intramuscular injection. Comes as lyophilized powder requiring reconstitution. Treatment given in courses rather than continuously. | Intranasal spray for behavioral effects. IV only in clinical settings. Sublingual also possible. Best used situationally rather than continuously. |
| Side Effects | Generally well-tolerated. May cause injection site reactions or mild allergic responses in sensitive individuals. | Intranasal: headache, nasal irritation, drowsiness. May cause over-attachment or emotional sensitivity. IV (clinical): uterine hyperstimulation, water retention. |
| Best For |
What They Have in Common
Both Cortexin and Oxytocin are commonly used for: