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BPC-157 & TB-500 & GHK-Cu vs SS-31 (Elamipretide)

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

BPC-157 & TB-500 & GHK-Cu

The complete healing triad combining the Wolverine Stack with GHK-Cu (copper peptide) for comprehensive tissue repair. This blend addresses healing at multiple levels: cellular repair, collagen synthesis, and tissue regeneration.

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SS-31 (Elamipretide)

SS-31, also known as Elamipretide or Bendavia, is a mitochondria-targeted tetrapeptide. It has been studied extensively for mitochondrial diseases, heart failure, and age-related decline in mitochondrial function.

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Side-by-Side Comparison

AspectBPC-157 & TB-500 & GHK-CuSS-31 (Elamipretide)
MechanismBPC-157 promotes angiogenesis and growth factor expression. TB-500 enhances cell migration and reduces inflammation. GHK-Cu activates genes involved in tissue remodeling, stimulates collagen and elastin production, and provides antioxidant protection. Together they support healing from multiple angles.Concentrates in the inner mitochondrial membrane where it binds to cardiolipin, stabilizing electron transport chain function, reducing reactive oxygen species, and improving ATP production efficiency.
Typical DosageTypical protocol: BPC-157 250-500mcg daily, TB-500 2-2.5mg twice weekly, GHK-Cu 1-2mg daily or applied topically for skin applications.Clinical trials have used IV infusions of 0.25mg/kg for acute conditions. Subcutaneous dosing protocols for research use typically range from 1-5mg daily.
AdministrationBPC-157 and TB-500 via subcutaneous injection. GHK-Cu can be injected subcutaneously or used topically depending on the target area. Systemic and local administration may be combined.Can be administered IV or subcutaneously. Most clinical research has used IV administration for cardiac conditions.
Side EffectsGenerally well-tolerated. Possible injection site irritation, mild fatigue, or temporary skin discoloration with GHK-Cu.Generally well-tolerated. Clinical trials reported injection site reactions and occasional headache.
Best For

What They Have in Common

Both BPC-157 & TB-500 & GHK-Cu and SS-31 (Elamipretide) are commonly used for:

Key Differences

Unique to SS-31 (Elamipretide):

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