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AOD-9604 & CJC-1295 & Ipamorelin vs MOTS-c

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

AOD-9604 & CJC-1295 & Ipamorelin

A targeted fat loss stack combining AOD-9604 (the fat-burning fragment of HGH) with CJC-1295 and Ipamorelin for comprehensive body recomposition. This blend addresses fat loss directly while supporting lean mass through GH optimization.

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MOTS-c

MOTS-c (Mitochondrial Open Reading Frame of the Twelve S rRNA type-c) is a mitochondrial-derived peptide that plays a key role in metabolic regulation and has emerged as a significant longevity research target.

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Side-by-Side Comparison

AspectAOD-9604 & CJC-1295 & IpamorelinMOTS-c
MechanismAOD-9604 stimulates lipolysis and inhibits lipogenesis without affecting IGF-1 or blood glucose. CJC-1295 and Ipamorelin provide sustained and pulsatile GH release to support metabolism and lean tissue. The combination targets fat loss through multiple mechanisms while preserving muscle.Activates AMPK pathway, enhances glucose uptake in skeletal muscle, improves insulin sensitivity, and regulates mitochondrial function. Acts as a metabolic hormone affecting whole-body energy homeostasis.
Typical DosageTypical protocol: AOD-9604 200-400mcg, CJC-1295 100-200mcg, Ipamorelin 100-200mcg daily. Usually administered in the morning fasted or before exercise.Research protocols typically use 5-10mg administered subcutaneously several times per week. Optimal dosing not yet established.
AdministrationSubcutaneous injection. Best administered fasted to maximize fat-burning effects. Can be taken as a pre-mixed blend or separate injections. Cycles typically run 8-16 weeks.Subcutaneous injection. Often combined with exercise protocols as it enhances exercise capacity and metabolic adaptation.
Side EffectsMild injection site reactions, headache, nausea. Generally well-tolerated as AOD-9604 lacks many HGH side effects.Limited human data. Animal studies show good tolerability. May affect energy levels and exercise performance.
Best For

What They Have in Common

Both AOD-9604 & CJC-1295 & Ipamorelin and MOTS-c are commonly used for:

Key Differences

Unique to MOTS-c:

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