AHK-Cu vs SNAP-8

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

AHK-Cu

AHK-Cu (Copper Tripeptide-3, Alanine-Histidine-Lysine Copper) is a copper peptide similar to GHK-Cu but with different properties. It's used for hair growth and skin rejuvenation applications.

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SNAP-8

SNAP-8 (Acetyl Octapeptide-3) is a cosmetic peptide that reduces the appearance of wrinkles by modulating muscle contraction. It is often called 'topical Botox' though it works through a different mechanism.

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Side-by-Side Comparison

AspectAHK-CuSNAP-8
MechanismThe copper-binding tripeptide stimulates collagen synthesis and may promote hair follicle enlargement. Works similarly to GHK-Cu but may have distinct receptor interactions.Mimics the N-terminal end of SNAP-25, competing with native SNAP-25 for position in the SNARE complex. This reduces neurotransmitter release at the neuromuscular junction, decreasing muscle contraction.
Typical DosageTopical: 0.5-2% concentration in serums for skin or scalp applications. Often combined with other growth factors for hair formulations.Topical: 3-10% concentration in serums or creams, applied 1-2 times daily to target areas (forehead, crow's feet, etc.).
AdministrationTopical application to skin or scalp. Can be used with microneedling for enhanced penetration. May cause temporary blue-green tint at high concentrations.Topical application only. Should be applied to clean skin. Often formulated with penetration enhancers for better absorption.
Side EffectsGenerally well-tolerated. May cause skin irritation in sensitive individuals. Temporary discoloration possible.Generally well-tolerated topically. Rare reports of mild skin irritation. No systemic effects at cosmetic doses.
Best For

What They Have in Common

Both AHK-Cu and SNAP-8 are commonly used for:

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