BPC-157 & TB-500
Known as the 'Wolverine Stack,' this popular combination pairs two powerful healing peptides. BPC-157 and TB-500 work synergistically to promote tissue repair, reduce inflammation, and accelerate recovery from injuries.
Mechanism of Action
BPC-157 upregulates growth factor expression and promotes angiogenesis, while TB-500 promotes cell migration and differentiation through actin regulation. Together, they enhance wound healing, reduce scar tissue formation, and support musculoskeletal recovery through complementary pathways.
Typical Dosage (Research)
Typical research protocols: BPC-157 at 250-500mcg daily combined with TB-500 at 2-2.5mg twice weekly during loading phase, then 2mg every 2 weeks for maintenance.
Both peptides administered via subcutaneous injection. Some protocols suggest injecting near injury sites for localized effects. Can be injected separately or as a pre-mixed blend.
Side Effects & Risks
Generally well-tolerated. May include mild nausea, temporary fatigue, headache, or localized irritation at injection sites.
Limited human clinical trial data for the combination. Theoretical concerns about promoting growth of existing cancers due to angiogenic properties. Not FDA approved for human use.
Who Uses BPC-157 & TB-500
Athletes recovering from injuries, individuals with tendon, ligament, or muscle damage, those seeking accelerated healing and reduced recovery time between training sessions.